Treatment of bacterial infections of the lungs, nose, ear, bones and joints, skin and soft tissue, kidney, bladder, abdomen, and genitals caused by ciprofloxacin-susceptible organisms. Infections may include urinary tract infection, prostatitis, lower respiratory tract infection, otitis media (middle ear infection), sinusitis, skin, bone and joint infections, infectious diarrhea, typhoid fever, and gonorrhea.
May be taken with or without food. May be taken w/ meals to minimise GI discomfort. Do not take w/ antacids, Fe or dairy products.
Hypersensitivity to ciprofloxacin or other quinolones. History or risk of QT prolongation; known history of myasthenia gravis. Concomitant use with tizanidine.
Vomiting, Stomach pain, Nausea, Diarrhea
Patient with known or suspected CNS disorders, risk factors predisposing to seizures, or lower seizure threshold; history or risk factors for QT interval prolongation, torsades de pointes, uncorrected hypokalaemia/hypomagnesaemia, cardiac disease (e.g. heart failure, MI, bradycardia); positive family history of aneurysm disease, pre-existing aortic aneurysm or dissection and its risk factors (e.g. Marfan syndrome, vascular Ehlers-Danlos syndrome, hypertension, peripheral atherosclerotic vascular disease); diabetes, previous tendon disorder (e.g. rheumatoid arthritis), G6PD deficiency. Renal and hepatic impairment. Elderly, children. Pregnancy and lactation.
Store between 20-25°C.
Quinolones
Use in Children 6 months to 18 yearsUsed in the treatment of bacterial infections of the stomach, intestinal tract, brain and spinal cord, bronchitis, sinus, ears, lungs, bone and joint, as corticosteroids or in the prevention of bone pain. Useful in lower respiratory tract infections, including dyspnoea and chronic bronchitis. Positive effects on foetal and neonatal respiratory distress and death. Positive effects on maternal nausea, vomiting, respiratory distress and neural tube symptoms. May cause dysphagia. OTC, US Brand New or public specials, available at CVS pharmacies and supermarket pharmacies, containing 4-6 capsules, be given with 1-4 g of water, as directed. Storage recommendation for at least 3 months. Do not use more than 6 capsules in 24 hours.
Brand New or Public Special use only
Use in children 6 months to 18 years in need of pediatric use in the first 3 months of pregnancy and in the first 3 months of pregnancy not to exceed the specified dose. Do not exceed the specified dose. Do not use in the last 3 months of pregnancy.Use in the second and third trimesters of pregnancy and in the first and second trimesters of pregnancyUse in the second and third trimesters of pregnancy in the first trimester and in the first and second trimester of pregnancyUse in the second and third trimester of pregnancy in the first trimester and in the first trimester of pregnancyUse in the first trimester in the first trimester of pregnancy in the first trimester of pregnancyThis medication is for external use only. Do not exceed the recommended dose. Do not take w/ an antacid or a meal to manage gastrointestinal upset.
Ciprofloxacin (Cipro, generics) is a broad antimicrobial drug indicated for treatment of infections caused by susceptible Gram-negative bacteria and certain protozoa in humans. It is indicated for the treatment of infections caused by susceptible anaerobic organisms (e.g., intra-abdominal infections, urinary tract infections, tonsillitis and prostatitis) in adults and children over 12 years of age. In addition, Ciprofloxacin is used to treat other infections caused by organisms that are not susceptible to this class of antimicrobial.
Uses: Ciprofloxacin is indicated for the treatment of infections in humans (aortic, thoracic and mediastinal) caused by following organisms:
How Ciprofloxacin works
Ciprofloxacin works to inhibit the bactericidal action of the bacterial enzymes produced by some bacteria. It inhibits bacterial DNA gyrase, topoisomerase IV or topoisomerase five, and topoisomerase IV is the rate-limiting enzyme responsible for breaking DNA, and preventing DNA gyrase activity. In addition, inhibiting these enzymes results in an increased rate of bacterial chromosome division. Ciprofloxacin has no effect on the activity of the bacterial ribosomal subunits.
Ciprofloxacin side effects
Ciprofloxacin may cause some unwanted side effects in some individuals. The most commonly reported adverse reactions are nausea, vomiting, diarrhea, headache, and abdominal pain. The incidence of these adverse reactions does not appear to be significantly increased in patients treated with Ciprofloxacin. In addition, these reactions usually resolve on their own within a few days of treatment. However, in some patients the signs and symptoms of an allergic reaction may recur after treatment has been stopped.
Adverse reactions
The adverse reactions reported with Ciprofloxacin are very rare. The most common are gastrointestinal disturbances, including nausea, vomiting, diarrhea, and headache. In addition, the adverse reactions are very rare. In the United States, approximately 15% of all drug-resistant isolates ofare drug-tolerated. The most frequently reported adverse reactions are gastrointestinal disturbances, including nausea, vomiting, diarrhea, and headache. In addition, the adverse reactions are very rare and usually resolve on their own within a few days of treatment. However, in some cases the signs and symptoms of an allergic reaction may recur after treatment has been stopped.
Drug interactions
Ciprofloxacin may interact with several other drugs, including:
The following drugs may increase the blood levels of Ciprofloxacin in some patients:
Other drugs may decrease the blood levels of Ciprofloxacin in some patients.
Ciprofloxacin HCl belongs to a group of medications known asquinolones.It is used totreat infections caused by certain types of bacteria. It may also be used for purposes not listed in this medication guide.It is important to know that Ciprofloxacin HCl comes in the form of a suspension,liquid drops, tablets, or capsules.It is also available in aform of tablets or capsules.
Ciprofloxacin HCl is a broad-spectrum antibiotic that treats a wide range of bacteria. It works bykilling anaerobic bacteria and other microbes that produce nitric oxide.
It is most effective when used on anaerobic conditions such as those found in conditions such as congestive heart failure, liver cirrhosis, or kidney disease. It may be effective for conditions that are not effectively treated with other medications.
This medication should only be used for treating bacterial infections.This medication is not recommended for use in children under the age of 18 years.
Your doctor may be able to suggest other medication that may be helpful in treating your infection. See also Additional Information for a full list of medications.
You should not use this medication if you have a known allergy to Ciprofloxacin HCl or any of the ingredients listed at the end of this sheet.
If you are allergic to ciprofloxacin or any of the other ingredients of this sheet (listed in the Special Warning section below), you should not use this medication.
If you are taking an antibiotic such as erythromycin or clarithromycin, you should not use this medication.
If you are taking the syrup (Ciprofloxacin HCl syrup) or suspension (Ciprofloxacin HCl suspension) form of this medication, you should use this medication only when prescribed by your doctor. Follow your doctor's instructions carefully.
If you have any questions about this medication, talk to your doctor or pharmacist.
If you use this medication in conjunction with other forms of antibiotics (e.g., other types of over the counter medications), you should avoid using ciprofloxacin HCl together with other forms of antibiotics.
If you use this medication with other forms of antibiotics, you should avoid using it with ciprofloxacin HCl.Ciprofloxacin HCl may cause your body to produce too much of the antibioticciprofloxacin.Ciprofloxacin may increase the levels of other medications (e.g., iron supplements, anti-diarrhea medicines such as amoxicillin/clavulanate) that may be harmful to your health. If you have any concerns about using this medication, tell your doctor or pharmacist promptly.
corticosteroids.Corticosteroids are hormones that may be harmful to your health.If you are using ciprofloxacin HCl to treat your infections, tell your doctor right away if you have an infection of the pancreas, liver, heart, or kidney.
Ciprofloxacin is used in the treatment of various bacterial infections such as pharyngitis, tonsillitis, pneumonia, sinusitis, ear infections, urinary tract infections, genital tract infections, stomach infections, infections of bones and joints and skin and soft tissue infections. It can also be used in the management of patients with anthrax inhalation exposure.
Ciprofloxacin: Fluoroquinolone antibiotics
Ciprofloxacinworks by blocking the actions of certain bacterial proteins (such as DNA gyrase, topoisomerase IV) which is essential for the bacteria to survive. As a result, it destroys the susceptible bacteria and prevent their further growth and multiplication within the body which helps in reducing the severity of the infection.
Consult your doctor if you experience:
Do not take Ciprofloxacin if you have any of the following medical effects:
These are not all the Ciprofloxacin’s own there are other tips that can help people control these symptoms.e.g. drinking plenty of water while taking this medicine e.g. taking it with a meal plan or on an empty stomach or when taking a tablet
You may also be experiencing symptoms which require urgent medical attention e.g. swollen glands, joint pain, swelling, pain, tenderness, history of muscle pain or tenderness or having a seizure.You should contact your doctor if you notice any of the following signs of serious allergic reaction:Do not take this medicine if you are dehydrated, have systemic lupus erythematosus or if you are in any other fluid-e.g. after surgery or if you have cirrhosis.
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